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Document Details
Document Type
:
Article In Journal
Document Title
:
Heart rate variability in patients with mitral stenosis: a study of 20 cases from King Abdulaziz University Hospital
Heart rate variability in patients with mitral stenosis: a study of 20 cases from King Abdulaziz University Hospital
Document Language
:
English
Abstract
:
BACKGROUND: Left atrial enlargement in mitral stenosis predisposes to atrial fibrillation (AF). Analysis of heart rate variability (HRV) prior to the onset of an arrhythmia may show alterations in autonomic balance that are known to predispose to the development of AF. The aim of this study was to determine whether HRV in patients with rheumatic mitral stenosis (MS) is abnormal in comparison to normal controls, and to find the relationship between left atrial size and HRV in patients with MS in sinus rhythm and in AF. SUBJECTS AND METHODS: A series of 24-hour ambulatory Holter electrocardiogram recordings were obtained for 10 consecutive, newly diagnosed untreated subjects with pure mitral stenosis in sinus rhythm, 10 with mitral stenosis complicated by atrial fibrillation and 10 age-matched normal controls. Digitized records were processed using time domain and power spectral analysis. RESULTS: In patients with mitral stenosis in sinus rhythm, we observed significant decrease of the standard deviation of the RR intervals (SDRR), as well as of the root mean square of successive RR interval differences (RMSSD) and Edinburgh index (sNN50), while in patients with AF, the RMSSD and sNN50 were much larger than those in normal. The areas under all spectral bands were markedly increased in patients with AF compared with normal. Furthermore, the high low frequency/high frequency (HLF/HF ratio) ratio was very small compared to normal. HRV measures were independent of atrial size in both groups. CONCLUSION: Decreased HRV in mitral stenosis patients with sinus rhythm suggests increased sympathetic activity in patients prone to atrial fibrillation, while marked increased of HRV in patients with AF may indicate that parasympathetic activity modulates the intrinsic behavior of the atrioventricular node during atrial fibrillation. The evaluation of HRV may be a useful tool for the identification of patients predisposed to AF
ISSN
:
0256-4947
Journal Name
:
Annals of Saudi Medicine
Volume
:
22
Issue Number
:
3
Publishing Year
:
1423 AH
2002 AD
Article Type
:
Article
Added Date
:
Saturday, October 17, 2009
Researchers
Researcher Name (Arabic)
Researcher Name (English)
Researcher Type
Dr Grade
Email
عودة الحازمي
Al-Hazimi, Awdah
Investigator
Doctorate
نبيل الأعمى
Al-Ama, Nabil
Researcher
Doctorate
مصطفى معروف
Marouf, Moustafa
Researcher
Doctorate
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28604.pdf
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